Brinzolamide
It is a carbonic anhydrase (CA) inhibitor sulphonamide drug which is used as 1% drops for topical treatment to lower intraocular pressure or glaucoma. EMEA and FDA have informed of very low serum levels found to be bound to CA red blood cells even after oral ingestion. For this reason and because it is usually used as a topical treatment its presence in mother’s milk is unlikely.
Like most ophthalmologic compounds for topical use, a low dose and poor absorption make it compatible with breastfeeding. Pressing conjunctiva sack for a couple of minutes to lessen systemic absorption.
Alternatives
- Dipivefrine Hydrochloride (Very Low Risk)
- Timolol (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.