Is Ciclopirox compatible with breastfeeding? Do we have alternatives for Ciclopirox?

Ciclopirox

April 17, 2016 (Very Low Risk)

Antifungal agent that is used as a component of creams, gels, suspensions or pessaries.

At latest update no published data were found on excretion into breast milk.

Less than 5% of the applied dose is absorbed.
Because the small dose used and low level achieved in the plasma of most topical dermatological preparations make unlikely the passage of significant amounts into breast milk.
Even more, its high plasma protein-binding capacity makes unlikely excretion into milk.

Do not apply on the chest to prevent infant ingestion; otherwise, apply it after a feeding and clean thoroughly with water before the next one.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • Ciclopirox Olamine

Writings

  • سيكلوبيروكس (Arabic)
  • Циклопирокс (Cyrillic)
  • 环吡酮 (Chinese)
  • シクロピロックス (Japanese)
  • C12H17NO2 (Molecular formula)

References

  1. SMI. Ciclopirox. Product Monograph. 2013 Full text (in our servers)
  2. Medea. Ciclopirox. Ficha técnica. 2010 Full text (in our servers)
  3. Leachman SA, Reed BR. The use of dermatologic drugs in pregnancy and lactation. Dermatol Clin. 2006Abstract
  4. Mactal-Haaf C, Hoffman M, Kuchta A. Use of anti-infective agents during lactation, Part 3: Antivirals, antifungals, and urinary antiseptics. J Hum Lact. 2001Abstract