Is Clenbuterol compatible with breastfeeding? Do we have alternatives for Clenbuterol?

Clenbuterol

September 4, 2014 (Low Risk)

Inhaled bronchodilator drugs are preferred because of a lower secretion into breast milk.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

References

  1. National Asthma Education and Prevention Program Asthma and Pregnancy Working Group. Managing asthma during pregnancy: recommendations for pharmacologic treatment-2004 update. 2004;1-57. 2004 Full text (link to original source) Full text (in our servers)
  2. Cazzola M, Testi R, Matera MG. Clinical pharmacokinetics of salmeterol. Clin Pharmacokinet. 2002Abstract
  3. Nelson-Piercy C. Asthma in pregnancy. Thorax. 2001Abstract Full text (link to original source) Full text (in our servers)
  4. McDonald CF, Burdon JG. Asthma in pregnancy and lactation. A position paper for the Thoracic Society of Australia and New Zealand. Med J Aust. 1996Abstract
  5. Ellsworth A. Pharmacotherapy of asthma while breastfeeding. J Hum Lact. 1994Abstract
  6. Yamamoto I, Iwata K, Nakashima M. Pharmacokinetics of plasma and urine clenbuterol in man, rat, and rabbit. J Pharmacobiodyn. 1985Abstract
  7. Lindberg C, Boréus LO, de Château P, Lindström B, Lönnerholm G, Nyberg L. Transfer of terbutaline into breast milk. Eur J Respir Dis Suppl. 1984Abstract
  8. Lönnerholm G, Lindström B. Terbutaline excretion into breast milk. Br J Clin Pharmacol. 1982Abstract Full text (link to original source) Full text (in our servers)
  9. Boréus LO, de Château PU. Terbutaline in breast milk. Br J Clin Pharmacol. 1982Abstract Full text (link to original source) Full text (in our servers)