Is Clonazepam compatible with breastfeeding? Do we have alternatives for Clonazepam?

Clonazepam

December 29, 2014 (Low Risk)

Intermediate-acting Benzodiazepine.

Excreted in low levels into breast milk. No adverse effect on breastfed infant has been reported.

However, some cases of high infant serum levels along with excessive somnolence and respiratory pauses when the mother started treatment at pregnancy were reported. Avoid use in preterm infants and early neonatal period.

Whether anxiolytic rather than anticonvulsivant treatment is intended, benzodiazepines with a shorter half-life span like Lorazepam or Oxazepam should be considered.

Eventual and low dose use of benzodiacepines are compatible with breastfeeding.

Use the short-acting benzodiazepine and minimal effective dose as possible mostly in the neonatal period.

WHO Model List of Essential Medicines (2002) rates it compatible with breastfeeding.

Follow-up for sedation and feeding ability of the infant.

Bed-sharing is not recommended for mothers who are taking this medication.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Drug trade names

References

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