Is Cloperastine compatible with breastfeeding? Do we have alternatives for Cloperastine?

Cloperastine

September 27, 2014 (Low Risk)

Cough relief medication with action on the Central Nervous System and mild anti-histamine effect, Piperidine derived drug with moderate sedative and anti-cholinergic effects.

At latest update, relevant information on excretion into breast milk was not found.

Product with a pharmacokinetics, effectiveness, therapeutic usefulness and side-effects that are ill defined. Authorized use in children.

Cough reflex is an important protection mechanism of the airway system. Use of symptomatic relief medication would be better avoided. Until more information on this medication is available, a known safer medication is preferred. Otherwise, sedation in the infant should be monitored.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Synonyms

  • クロペラスチン
  • Cloperastine Fendizoate
  • Cloperastine Hydrochloride
  • Levocloperastine
  • كلوبيراستين
  • Клоперастин
  • 氯哌斯汀

References

  1. Catania MA, Cuzzocrea S. Pharmacological and clinical overview of cloperastine in treatment of cough. Ther Clin Risk Manag. 2011Abstract Full text (link to original source) Full text (in our servers)
  2. Cloperastina. Ficha técnica. 2011 Full text (in our servers)
  3. Cloperastina. Ficha técnica. 2007 Full text (in our servers)
  4. Aliprandi P, Castelli C, Bernorio S, Dell'Abate E, Carrara M. Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents. Drugs Exp Clin Res. 2004Abstract
  5. Canti G, Franco P, Nicolin A. [The pharmacologic activity of 1(2-(p-chloro-alpha-phenylbenzyloxy)ethyl)piperidine (cloperastine)]. Boll Chim Farm. 1983Abstract