Is Dihydroergotamine compatible with breastfeeding? Do we have alternatives for Dihydroergotamine?


December 28, 2013 (High Risk)

Ergot derivative alkaloid. It may inhibit prolactin secretion.

It is used together with other substances (e.g. caffeine, which is a cause of anxiety). Multiple drug association is not recommended.

On latest update relevant data on breastfeeding was not found.

Sumatriptan which is a drug with well known low excretion into breast milk should be an alternative treatment for Migraine.


Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.


  1. Bordini CA, Roesler C, Carvalho Dde S, Macedo DD, Piovesan É, Melhado EM, Dach F, Kowacs F, Silva Júnior HM, Souza JA, Maciel JA Jr, Carvalho JJ, Speciali JG, Barea LM, Queiroz LP, Ciciarelli MC, Valença MM, Lima MM, Vincent MB. Recommendations for the treatment of migraine attacks - a Brazilian consensus. Arq Neuropsiquiatr. 2016Abstract Full text (link to original source) Full text (in our servers)