Human Menopausal Gonadotrophins
A natural hormone present in the urine of menopausal women which has the activity of follicle stimulating hormone (FSH) and luteinizing hormone (LH). When these hormones, FSH and LH, are in a 1:1 ratio, the product is known as menotropin.
Administration by subcutaneous or intramuscular injection.
Indicated to stimulate ovulation in assisted reproduction techniques.
Since the last update we have not found published data on its excretion in breastmilk.
Its high molecular weight makes it very unlikely it will transfer into milk in significant quantities.
Due to its protein nature it is inactivated in the gastrointestinal tract, not being absorbed, so its oral bioavailability is practically nil, except in premature babies and the immediate neonatal period when there may be greater intestinal permeability.
No adverse effects have been recorded in infants.
In infertility treatments, the possible theoretical anovulatory effect of frequent on demand breastfeeding must be taken into account.
See below the information of these related products:
- Choriogonadotropin Alfa (Low Risk probable)
- Follitropin (Low Risk probable)
- Human Chorionic Gonadotrophin (Low Risk probable)
- Lutropin (Low Risk probable)
Alternatives
We do not have alternatives for Human Menopausal Gonadotrophins.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Follitropin (FSH) + Lutropin (LH)
- Menotropin (FSH:LH = 1:1)
- Urogonadotrophin
Writings
- Εμμηνοπαυσιακές γοναδοτροπίνες ανθρώπινες (Greek)
- ヒト下垂体性性腺刺激ホルモン (Japanese)
- C1014 H1609 N287 O294 S27 (Molecular formula)
- HMG (Abbreviation)
- G03GA02 (ATC Code/s)
References
- AEMPS. Menotropina (Menopur) 2015 Full text (in our servers)
- Ferring. Menotropin (Menopur). Drug Summary. 2008 Full text (in our servers)