Is Pridinol Mesilate compatible with breastfeeding? Do we have alternatives for Pridinol Mesilate?

Pridinol Mesilate

August 6, 2018 (High Risk)

Centrally acting muscle relaxant with anticholinergic effects.

At last update no published on excretion in breast milk data were found. Even on humans pharmacokinetic data is barely found.

Its anticholinergic effect has a theoretical risk of inhibiting lactation especially during the early postpartum weeks.

Until more data about this drug regarding breastfeeding is available, safer known alternatives should be of choice, especially in the neonatal period and in case of prematurity.

If administered during breastfeeding, use small doses and monitor drowsiness and adequate feeding of the infants.

(Not to be confused with the trademark Pridinol, which in some countries corresponds to Terfenadine)

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • Придинола Мезилат (Greek)
  • プリジノールメシル酸塩 (Japanese)
  • C2 0H25 NO,CH3 SO3 H (Molecular formula)
  • 1,1-Diphenyl-3-piperidinopropan-1-ol methanesulphonate (Chemical name)
  • M03BX03 (ATC Code/s)

References

  1. Bago. Pridinol. Ficha técnica. 2000 Full text (in our servers)