Procaine Hydrochloride
At latest update no published data on excretion into breast milk was found.
Topical anesthetics (dermatological and mouth preparations when correctly applied like creams, subcutaneous injections for infiltration or spinal anesthesia) have negligible systemic absorption.
Pharmacokinetic data (poor absorption and short half-life span) make it highly unlikely the passage into milk in significant amount.
Do not apply it on the chest or, whenever necessary, apply it after having nursed the baby and clean it thoroughly up with water before the next meal.
Having been published less experience than with other drugs of the same group, it would be preferable the use of a known safer alternative, especially during the neonatal period and in case of premature birth.
Alternatives
- Ropivacaine (Very Low Risk)
- Pramocaine (Very Low Risk)
- Lidocaine (Very Low Risk)
- Benzocaine (Very Low Risk)
- Prilocaine (Very Low Risk)
- Tetracaine (Very Low Risk)
- Bupivacaine (Very Low Risk)
- Articaine (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Allocaine
- Syncaine
Writings
- Прокаина Гидрохлорид (Cyrillic)
- プロカイン塩酸塩 (Japanese)
- C13H20N2O2,HCl (Molecular formula)
References
- AEMPS. Procaína. Ficha técnica. 2007 Full text (in our servers)
- WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)