Is Rizatriptan compatible with breastfeeding? Do we have alternatives for Rizatriptan?

Rizatriptan

November 14, 2014 (Low Risk)

On latest update relevant data on breastfeeding was not found.

Similar to Sumitriptan composition which is known to have a low excretion into breast milk.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

References

  1. Duong S, Bozzo P, Nordeng H, Einarson A. Safety of triptans for migraine headaches during pregnancy and breastfeeding. Can Fam Physician. 2010Abstract Full text (link to original source) Full text (in our servers)
  2. Jürgens TP, Schaefer C, May A. Treatment of cluster headache in pregnancy and lactation. Cephalalgia. 2009Abstract
  3. Marcus DA. Managing headache during pregnancy and lactation. Expert Rev Neurother. 2008Abstract
  4. Raña-Martínez N. [Migraine in females]. Rev Neurol. 2008Abstract
  5. Beseler-Soto B, Paricio-Talayero JM, Sánchez-Palomares M, Benlloch-Muncharaz M, Santos-Serrano L, Landa-Rivera L. [Migraine and female]. Rev Neurol. 2008Abstract
  6. MacGregor EA. Migraine in pregnancy and lactation: a clinical review. J Fam Plann Reprod Health Care. 2007Abstract Full text (in our servers)
  7. Loder E. Migraine in pregnancy. Semin Neurol. 2007Abstract
  8. Rizatriptan Ficha técnica 2007 Full text (in our servers)
  9. Sances G, Granella F, Nappi RE, Fignon A, Ghiotto N, Polatti F, Nappi G. Course of migraine during pregnancy and postpartum: a prospective study. Cephalalgia. 2003Abstract
  10. Allais G, Bosio A, Mana O, Airola G, Ciochetto D, Terzi MG, De Lorenzo C, Quirico PE, Benedetto C. [Migraine during pregnancy and lactation: treatment of the acute attack and non-pharmacological prophylactic strategies]. Minerva Med. 2003Abstract
  11. Rathmell JP, Viscomi CM, Ashburn MA. Management of nonobstetric pain during pregnancy and lactation. Anesth Analg. 1997Abstract
  12. Wojnar-Horton RE, Hackett LP, Yapp P, Dusci LJ, Paech M, Ilett KF. Distribution and excretion of sumatriptan in human milk. Br J Clin Pharmacol. 1996Abstract