Is Azelastine compatible with breastfeeding? Do we have alternatives for Azelastine?

Azelastine

June 30, 2015 (Low Risk)

Second generation anti-histaminic drug with low sedative effect. Used for ophthalmic and nasal topical administration.

On last update no relevant published data related to breastfeeding were found.

A small dose together with a low plama level of most nasal and ophthalmologic compounds make that a significant excretion into breast milk would be unlikely.

Alternatives

Loratadine (Very Low Risk)
Cetirizine Hydrochloride (Very Low Risk)

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

Азеластина (Cyrillic)
アゼラスチン (Japanese)

References

So M, Bozzo P, Inoue M, Einarson A. Safety of antihistamines during pregnancy and lactation. Can Fam Physician. 2010Abstract Full text (link to original source) Full text (in our servers)
Ito S, Blajchman A, Stephenson M, Eliopoulos C, Koren G. Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. Am J Obstet Gynecol. 1993Abstract