Is Doxazosin Mesylate compatible with breastfeeding? Do we have alternatives for Doxazosin Mesylate?

Doxazosin Mesylate

June 4, 2016 (Very Low Risk)

It is excreted into breast milk in clinically non-significant amount possibly due to its high plasma protein binding capacity.

Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug may be used, especially during the neonatal period and/or in case of premature infants.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • Δοξαζοσίνη Μεθανοθειονική (Greek)
  • Доксазозина Мезилат (Cyrillic)
  • ドキサゾシンメシル酸塩 (Japanese)
  • C23H25N5O5,CH3SO3H (Molecular formula)

References

  1. Anderson PO. Treating Hypertension During Breastfeeding. Breastfeed Med. 2018Abstract
  2. Jensen BP, Dalrymple JM, Begg EJ. Transfer of doxazosin into breast milk. J Hum Lact. 2013Abstract
  3. Elliott HL, Meredith PA, Reid JL. Pharmacokinetic overview of doxazosin. Am J Cardiol. 1987Abstract