Is Rofecoxib compatible with breastfeeding? Do we have alternatives for Rofecoxib?
Rofecoxib
July 1, 2015 (High Risk)
Medication indicated for treatment of Arthritis, acute pain and Primary Dysmenorrhea. It acts by blocking the activity of enzyme cyclooxygenase (COX-2).
Excretion into breast milk is insignificant.
Withdrawn from the world market since 2004, because an observed higher risk for severe cardiovascular damage (myocardial infarction, ictus) among patients who were treated for longer than one year.
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Writings
- روفيكوكسيب (Arabic)
- Рофекоксиб (Cyrillic)
- 罗非考昔 (Chinese)
- ロフェコキシブ (Japanese)