Is Rupatadine Fumarate compatible with breastfeeding? Do we have alternatives for Rupatadine Fumarate?

Rupatadine Fumarate

February 15, 2016 (Low Risk)

Second generation antihistamine and piperidine-type compound, without the sedative and anticholinergic effects of first generation antihistaminics.

Pharmacokinetic data (moderately high molecular weight and high percentage of protein binding) make it unlikely an excretion into breast milk in significant amounts.

Until more published data on this drug regarding breastfeeding is available, safer alternatives of better known drugs should be preferable, especially during the neonatal period and in case of prematurity.

Follow-up the baby for drowsiness and inappropriate infant feeding.

Alternatives

Very Low Risk

Compatible. Not risky for breastfeeding or infant.

Low Risk

Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.

High Risk

Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.

Very High Risk

Not recommended. Cessation of breastfeeding or alternative.

Writings

  • روباتادين (Arabic)
  • Рупатадина Фумарат (Cyrillic)
  • 芦帕他定 (Chinese)
  • ルパタジンフマル酸塩 (Japanese)
  • C26H26ClN3,C4H4O4 (Molecular formula)

Drug trade names

References

  1. AEMPS. Rupatadina. Ficha técnica. 2015 Full text (in our servers)
  2. So M, Bozzo P, Inoue M, Einarson A. Safety of antihistamines during pregnancy and lactation. Can Fam Physician. 2010Abstract Full text (link to original source) Full text (in our servers)