Alcuronium Chloride
It is a non-depolarizing muscle relaxant drug with a peripheral action that is used as premedication for endotracheal intubation and general anesthesia. A product that is rarely used with very few bibliographic references.
At latest update, no relevant published data concerning excretion into breast milk were found.
Like other blocking drugs from the same family, its relatively high molecular weight would decrease excretion into breast milk.
Other well-known and safer options should be preferred until more information on this drug is available.
List of Essential Medicines of the WHO: compatible with breastfeeding.
Alternatives
- Atracurium (Very Low Risk)
- Mivacurium (Very Low Risk)
- Rocuronium (Very Low Risk)
Very Low Risk
Compatible. Not risky for breastfeeding or infant.
Low Risk
Moderately safe. Mild risk possible. Follow up recommended. Read the Comment.
High Risk
Poorly safe. Evaluate carefully. Use a safer alternative. Read the Comment.
Very High Risk
Not recommended. Cessation of breastfeeding or alternative.
Synonyms
- Diallylnortoxiferine Dichloride
- Ro-4-3816
- كلوريد ألكورونيوم
- Αλκουρόνιο χλωριούχο
- Алкурония Хлорид
- 塩化アルクロニウム
- 阿库氯铵
Drug trade names
References
- WHO / UNICEF. BREASTFEEDING AND MATERNAL MEDICATION Recommendations for Drugs in the Eleventh WHO Model List of Essential Drugs. Department of Child and Adolescent Health and Development (WHO/UNICEF) 2002 Full text (link to original source) Full text (in our servers)
- Ho PC, Stephens ID, Triggs EJ. Caesarean section and placental transfer of alcuronium. Anaesth Intensive Care. 1981Abstract
- Walker J, Shanks CA, Triggs EJ. Clinical pharmacokinetics of alcuronium chloride in man. Eur J Clin Pharmacol. 1980Abstract